The 1952 United States Senate election in Missouri was held on November 4, 1952.
Incumbent Republican Senator James P. Kem ran for re-election to a second term in office, but was defeated by Secretary of the Air Force Stuart Symington.
Republican primary
Candidates
- Herman G. Grosby
- James P. Kem, incumbent Senator since 1947
- William McKinley Thomas, perennial candidate
Results
Democratic primary
Candidates
- John A. Johnson, State Senator from Ellington
- Stuart Symington, U.S. Secretary of the Air Force
- J.E. "Buck" Taylor, Missouri Attorney General
Results
General election
Results
See also
- 1952 United States Senate elections
References


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